Long-range fibre damage in small vessel brain disease affects aphasia severity
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چکیده
منابع مشابه
Brain Atrophy and Cerebral Small Vessel Disease
Background and Purpose—Cerebral small vessel disease (SVD) is the most common cause of vascular dementia. Interest in the use of surrogate markers is increasing. The aims of this study were to determine if brain volume was different between patients with SVD and control subjects, whether it correlated with cognition in SVD, and whether changes in brain volume could be detected during prospectiv...
متن کاملBlood-brain barrier permeability and long-term clinical and imaging outcomes in cerebral small vessel disease.
BACKGROUND AND PURPOSE Increased blood-brain barrier (BBB) permeability occurs in cerebral small vessel disease. It is not known if BBB changes predate progression of small vessel disease. METHODS We followed-up patients with nondisabling lacunar or cortical stroke and BBB permeability magnetic resonance imaging after their original stroke. Approximately 3 years later, we assessed functional ...
متن کاملClinical Interaction between Brain and Kidney in Small Vessel Disease
Patients with chronic kidney disease (CKD) are well known to have a higher prevalence of cardiovascular disease from epidemiological studies. Recently, CKD has also been shown to be related to neurological disorders, not only ischemic brain injury but also cognitive impairment. This cerebrorenal connection is considered to involve small vessel disease in both the kidney and brain, based on thei...
متن کاملBrain hemorrhage recurrence, small vessel disease type, and cerebral microbleeds
OBJECTIVE We evaluated recurrent intracerebral hemorrhage (ICH) risk in ICH survivors, stratified by the presence, distribution, and number of cerebral microbleeds (CMBs) on MRI (i.e., the presumed causal underlying small vessel disease and its severity). METHODS This was a meta-analysis of prospective cohorts following ICH, with blood-sensitive brain MRI soon after ICH. We estimated annualiz...
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ژورنال
عنوان ژورنال: Brain
سال: 2019
ISSN: 0006-8950,1460-2156
DOI: 10.1093/brain/awz251